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Disease is an abnormal life activity process that occurs due to the disorder of homeostasis under the damaging action of a certain cause. It belongs to a specific abnormal pathological situation and will affect the structure and function of some or all tissues, organs and systems of the organism. Nowadays, more and more people are suffering from various diseases in the world, which have a huge impact on people's work and life.
Infectious Disease
Infectious disease is a general term for many kinds of diseases that are caused by pathogens that can be transmitted from person to person, animal to animal, or human to animal. The most common ones are influenza, hepatitis B, bacterial dysentery, tuberculosis, and acute hemorrhagic conjunctivitis (pink eye), etc.
Non-infectious Disease
Malignant tumor is cancer, which is a collective term for more than 100 related diseases. When a cell in the body mutates, it divides continuously, out of the body's control, and eventually forms cancer. Prompt diagnosis can go a long way in improving the survival rate of cancer patients.
Autoimmune disease (AID) refers to the disease caused by the body's immune response to self-antigens, resulting in damage to its own tissues. Common autoimmune diseases are systemic lupus erythematosus and rheumatoid arthritis. The global prevalence of autoimmune diseases ranges from 5% to 20%. Incidence and prevalence have increased significantly over the past 30 years. Autoimmune diseases are one of the top 10 leading causes of death in women under the age of 64.
Cardiovascular disease refers to diseases of the heart or blood vessels, also known as diseases of the circulatory system, including atherosclerosis, thrombosis, myocardial/cerebral infarction and subsequent ischemia-reperfusion injury, and is a leading cause of disability and death worldwide. More than four-fifths of cardiovascular deaths are due to heart attacks and strokes, and one-third of these deaths occur in people under the age of 70.
Nervous system diseases refer to diseases that occur in the central nervous system and peripheral nervous system and are mainly manifested by sensory, motor, consciousness, and neurological dysfunction. Chronic diseases account for the majority of neurological diseases, which are often incurable for a long time, which has a great impact on the work and life of patients, and has a high disability rate. Common neurological disorders include Alzheimer's disease, Parkinson's disease, epilepsy, and migraine headaches.
Accurate and timely disease diagnosis is a prerequisite for effective treatment and intervention. Different diseases have different diagnostic methods, but the main ones commonly used in clinical practice are imaging examination, pathological examination, biomarker testing, and molecular diagnosis, etc.
For example, autoimmune diseases are usually detected by testing autoantibodies, and neurological diseases are usually diagnosed by cerebrospinal fluid analysis and imaging tests, the primary diagnostic methods for cardiovascular disease include echocardiography, ambulatory blood pressure testing, myocardial scans, and various vasoactive substance tests. In addition, biosensing technology based on CRISPR-Cas system can also be used for disease diagnosis due to its high specificity and high sensitivity.
Utilizing the DeteCasTM platform based on the CRISPR-Cas system, CD BioSciences can provide various services in disease diagnosis, such as nucleic acids detection service, protein biomarker detection service and small molecule detection service. If you are interested in these services, please contact us.
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