Nucleic Acid Detection Kit Development Service

Due to its unique advantages, the CRISPR-Cas system has been used for nucleic acid detection. CD BioSciences, a premier biotechnology company, is committed to providing you with development services for nucleic acid detection kits based on the CRISPR-Cas system.

Nucleic Acid Assay Kit Development Service

CRISPR-Cas System-Based Nucleic Acid Detection Kit

Nucleic acid detection technology has a crucial role in the diagnosis of infections, genetic diseases and cancers. The CRISPR-Cas system has shown promising applications in the field of nucleic acid detection due to its unique precise recognition as well as the accompanying cleavage ability. In recent years, by coupling with nucleic acid amplification technology, the CRISPR-Cas system has increasingly become a favorable tool for nucleic acid detection.

Principle of CRISPR-Cas System-Based Nucleic Acid Detection Kit Development
The novel nucleic acid detection technologies currently developed based on the CRISPR-Cas system are based on the specific recognition of target nucleic acid sequences by nucleic acids or probes, which amplify and convert biological signals into easily detectable physicochemical signals. Nucleic acid detection kits developed based on CRISPR technology can be used in various scenarios, such as pathogen detection, disease diagnosis, food safety and environmental contaminant monitoring.

COVID-19 Test Kit

COVID-19 Test Kit

To contain the spread of new coronaviruses and to prevent outbreaks of novel infectious diseases, countries around the world are stepping up the development of various novel rapid detection technologies. Currently, a number of neo-coronavirus detection kits based on the CRISPR-Cas system have been developed. They can be used for in vitro qualitative detection of the novel coronavirus (SARS-CoV-2) N gene in respiratory samples from suspected cases of pneumonia with novel coronavirus infection, patients with suspected aggregated cases, and others who require diagnosis or differential diagnosis of novel coronavirus infection.

Our Services

Utilizing the CRISPR-Cas system's ability to specifically identify and incidentally cleave nucleic acid sequences, our DeteCas^TM platform offers nucleic acid detection kit development service. In addition, we also provide services for the detection of various analytes such as nucleic acids, protein biomarkers, metal ions, and small molecules.

Types of Developed Detection Kits

DNA Detection Kit

RNA Detection Kit

Service Details

Feasibility Study

Preliminary determination of methods
Preliminary standard curve establishment

Reagent Kit Development

Optimization of reagent kit reaction conditions and parameters
Standard curve determination

Validation of Reagent Kit

Sensitivity determination
Intra-batch and inter-batch variation determination
Additive recovery measurement
Sample measurement, etc.

Reagent Kit Production

Supply of kit

Applications

Pathogen Detection

Food Safety Detection

Environmental Monitoring

Process of Our Service

Advantages of Our Service

Wide Detection Range

The developed assay kit can detect nucleic acids molecules in different species and cell compartments.

Highly Sensitive

Nucleic acid substrates can be detected at concentrations as low as 10^-18 mol/L.

Easy to Operate

The kits are easy to use and operator friendly because of the greatly simplified assay process.

CD BioSciences provides affordable, qualified and hassle-free nucleic acid detection kit development service to our global clients. We guarantee on-time delivery of results. We are available to you 24 hours a day, so please feel free to contact us.

References

Hatoum-Aslan, A. CRISPR methods for nucleic acid detection herald the future of molecular diagnostics. Clinical Chemistry. 2018, 12(64): 1681–1683.
Tina, Y.L., et al. Accelerated RNA detection using tandem CRISPR nucleases. Nature Chemical Biology. 2021, 17:982-988.

For research use only. Not intended for any clinical use.